Methamphetamine is truly dangerous because even a single use collapses the dopamine system

If the maximum dopamine level our nerves can withstand is 100,
and the maximum level achievable in a normal life is 80,
methamphetamine shoots it up to 200 all at once.
In short, you can think of it as all your dopamine receptors being burned away.
Psychiatric disorders such as depression or hallucinations are just a bonus.
You can also acquire skin and periodontal diseases like meth mouth and meth bug.